Скачать или смотреть LEARN ABOUT ACLIDINIUM, A LONG ACTING ANTICHOLINERGIC FOR COPD

Welcome to clinicals with Pharm Vic. Today we will be learning about Aclidinium.
This medication belongs to the class of medicine called Long acting Anticholinergics
(inhaled)
Mode of action
Promote bronchodilation by inhibiting cholinergic bronchomotor tone. They block
muscarinic actions of acetylcholine.
Indications
COPD
Precautions
Cardiovascular disorders—anticholinergics may increase risk of cardiovascular adverse
effects; patients with pre-existing cardiac conditions were often excluded from
randomised, controlled trials.
Risk factors for angle-closure glaucoma—acute angle-closure crisis may rarely be
precipitated.
Bladder outlet obstruction—symptoms may worsen.
Pregnancy
Limited experience; not expected to be a concern.
Breastfeeding
Safe to use.
Adverse effects
Common
headache, nasopharyngitis
Adverse effects from Anticholinergics
Common
dry mouth, throat irritation
Infrequent (0.1–1%)
blurred vision, dizziness (common for ipratropium), urinary retention
Rare
constipation, acute angle-closure crisis, palpitations, allergy (eg urticaria, rash,
angioedema, anaphylaxis)