AOH1996 treatment targeting PCNA shows promise for reoccurring solid tumours

Описание к видео AOH1996 treatment targeting PCNA shows promise for reoccurring solid tumours

Dr Linda Malkas speaks to ecancer about her talk at AACR 2023 on AOH1996, a cancer medicine, which targets PCNA and shows promise in treating cancer patients with reoccurring solid tumours.

She outlines the background and design of the trial.

Dr Malkas explains they identified a potent PCNA inhibitor (AOH1996). The results showed AOH1996 selectively kills many types of cancer cells at below micromolar concentrations without causing significant toxicity to a broad range of non-malignant cells.

This highlights the potential of AOH1996 as a broad-spectrum therapeutic agent for the treatment of many types of cancer patients with solid tumours.

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