[Hero Siege 2] Season 4.5 Plague Doctor Wormhole 153 clear (334.5 Billion HP Boss).

Each of these mobs is tougher than any of Uber bosses...
This video is a showcase of hardest content in the game (currently highest wormhole from all classes ladder) which Surgical Blood Letting Plague Doctor is capable of clearing and also showing that (sadly) you don't need endgame gear for anything in the game aside of this type of activity which gives you nothing but ladder placement. This Boss has almost 45 times more HP than pinncle boss - Gabriel, and to be honest i think every monster in this wormhole had more HP too.
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LINKS:

ENDGAME guide with useful links and build (updated for 4.5 both melee and range options):
https://docs.google.com/spreadsheets/...

DPS explained with DPS calculator: https://docs.google.com/spreadsheets/...

If you have any questions left, ask them in official Hero Siege discord, in Plague Doctor community and read pinned comments there.