Calcium channel blockers for anxiety?

Many people with anxiety disorders don't respond well to standard treatments. The pace of drug discovery is slow when it comes to new treatments for anxiety.

Calcium channels are pore-like proteins that allow calcium to enter cells. Drugs that block the calcium channel are usually used to treat high blood pressure. They can also be useful to prevent migraine headaches. A handful of data suggests that some of them might be useful at reducing anxiety or preventing panic attacks.

This lecture examines the evidence for calcium channel blockers as possible tools in the treatment of anxiety.

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📘 Chapters 📘
0:00 Could calcium channel blockers be good for anxiety?
0:33 Lavender oil might include a calcium channel blocker
1:24 What are calcium channels
3:27 How does calcium affect cells?
5:06 Calcium affects neurotransmitter release
6:06 Calcium channels links to psychiatric symptoms
7:06 Calcium channel blockers and reduced depression risk
8:09 Calcium channel blockers may reduce bipolar mania
9:24 Neurontin and Lyrica are calcium channel blockers
10:24 Do calcium channel blockers for blood pressure work for anxiety?
10:42 Case reports of calcium channel blockers for anxiety or panic attacks
11:10 Placebo-controlled study of verapamil for anxiety or panic attacks
12:33 Calcium channel blockers and brain blood flow
13:34 Nimodipine reduced panic attacks in people with reduced brain blood flow
14:04 One-time dosing did not work
14:49 Case report of calcium channel blocker causing anxiety
14:58 Summary
16:52 The psychiatric value of calcium channel blockers is poorly understood

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