Скачать или смотреть İON 481. Lecture, Yağmurlu: White Matter Anatomy and its Role in the Spread of IIntra-Axial Tumors

Gliomas dissemination occurs much faster along the white matter bundles than trough cortical areas. Glioma cells actively migrate through the tortuous extracellular spaces of the brain, which leads to the formation of distant satellite tumors. Hence, they behave much like non-malignant brain cells during embryonic development, or adult stem cells in the mature brain, which similarly migrate along extracellular routes, often exploiting nerve bundles as guides. Some studies even suggest that a difference in the direction of the white matter bundles (parallel or perpendicular to the tumor front cells) may influence the gliomas infiltration in different ways and velocities. The initial tumor location and the architecture of the peritumoral tissue are therefore very important for the comprehension and prediction of the possible infiltration patterns.

Dr. Kaan Yağmurlu is giving "White Matter Anatomy and its Role in the Spread of Intra-Axial Tumors" lecture, don’t miss it!