Скачать или смотреть How splicing neoantigens expands tumor landscape for immunotherapy

Darwin Kwok, PhD, University of California, San Francisco, CA, comments on the potential of splicing neoantigen targeting to complement existing immunotherapy strategies. Dr Kwok suggests that splicing neoantigen targeting could enhance the specificity and potency of immunotherapies by selectively targeting tumor-specific splicing variants. However, he also highlights the need to overcome technical hurdles, including the development of efficient and scalable methods for identifying and isolating these variants, as well as the optimization of delivery systems to ensure effective tumor penetration. This interview took place during the 2025 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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