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Can Trulicity be used with insulin Yes Trulicity can be used with insulinThe dosage of insulin may need to be reducedThe combination of Trulicity and insulin increases the risk of low blood sugar levels hypoglycemiaTrulicity is only suitable for people with type diabetes who still have functioning insulinproducing cells in their pancreasTrulicity is given by subcutaneous injection once a week The injection site for Trulicity and insulin should be spaced apartTrulicity dulaglutide mimics the action of GLP a naturally occurring hormone that helps to regulate blood glucose levels It may be used for the treatment of type diabetes in adults over the age of or to reduce the risk of major adverse cardiovascular events such as a heart attack or stroke occurring in adults with type diabetes who already have cardiovascular disease or are at high risk of cardiovascular diseaseInsulin is a hormone that is produced naturally in our bodies There are several different types of insulin and each one has been made to last for a specific length of time This allows doctors to prescribe a dosing schedule that better replicates the natural release of insulin by the body in response to foodBoth Trulicity and insulin are given by subcutaneous injection just under the skin Trulicity is given once a week and the dosing schedule for insulin varies depending on the person but may be given once to several times per day Some people use an insulin pump which injects insulin continuouslyAvoid injecting Trulicity into the same area of skin that you have previously injected insulin Try to ensure at least to inches to cm of skin is between the two sites Do not use a site where the skin is discolored bruised broken covered with a psoriatic lesion or has a rash You can inject into the skin on your thigh stomach area except for a inch cm area around your belly button or the outer area of your upper armRelated questions Toujeo vs Lantus Whats the difference between them How and where should I inject insulin Is Trulicity a form of insulin How does Trulicity workTrulicity mimics the action of GLP a naturally occurring hormone that helps to regulate blood glucose levelsTrulicity contains of the same amino acid sequence as naturally occurring GLP This enables it to bind to and activate GLP receptors which stimulates insulin secretion and lowers glucagon secretion when blood glucose levels are high It also causes a slowing down in how fast the stomach emptiesTrulicity is given by subcutaneous under the skin injection into your stomach thighs or upper arm once a week and may be used for the treatment of type diabetes Trulicity does not work for type diabetesTrulicity is not a form of insulin It relies on people still having some functioning beta cells these are cells in the pancreas that produce store and release insulinTrulicity belongs to the class of medicines known as GLP receptor agonists It may also be called an incretin mimeticHow does insulin workInsulin is produced stored and released by beta cells in the pancreas People with type diabetes have very few functioning beta cells The beta cells in people with type diabetes usually retain some function at least initially but as their diabetes progresses their ability to produce insulin decreasesThe main role of insulin is to allow cells throughout the body to uptake glucose sugar and convert it into a form that can be used by these cells for energy Without insulin we cannot survive and death from diabetes was a common occurrence until insulin was discovered in the early s by Frederick Banting and Charles Best