Скачать или смотреть ADaM Mapping Specification for ADRS | Deriving Best Overall Response (BOR PARAMCD) Step-by-Step

In this video, I explain how to create an ADaM mapping specification for the ADRS domain specifically for Best Overall Response (BOR – PARAMCD) in oncology clinical trials.

You will learn how to derive BOR by systematically using:

aCRF annotations

Raw source datasets

SDTM datasets (TR, RS, TU, etc.)

SAP / Protocol rules

This video walks through the end-to-end thought process required to document a clear, reviewer-ready ADaM mapping specification, which is essential for regulatory submissions and interviews.

🔍 Topics covered:

What is ADRS and where BOR fits in ADaM

Understanding BOR definition from the SAP

Identifying source data from aCRF and raw datasets

Mapping BOR from SDTM response domains

Handling assessment windows and confirmation rules

Creating PARAM / PARAMCD for BOR

Writing derivation logic and traceability

Common mistakes and best practices in BOR mapping

This video is especially useful for:

Clinical SAS Programmers

ADaM Programmers

Oncology trial programmers

CDISC interview preparation

Anyone working on ADRS and efficacy endpoints

📌 If you are preparing for interviews or working on oncology ADaM datasets, this video will help you understand both the concept and documentation approach.