Скачать или смотреть Loo-Riegelman Method BPPK

In this video, we break down the Loo-Riegelman Method, which is specially used for 2-compartment pharmacokinetic models when the drug is given by the oral (extravascular) route.
This method helps estimate Ka (Absorption Rate Constant) accurately when Wagner–Nelson fails for multi-compartment drugs.

📌 What’s covered in the video:

What is Loo-Riegelman Method?

Why Wagner–Nelson cannot be used for 2-compartment drugs

Ab = Xc + Xt + X3 explained

Using AUC to calculate X3

Fraction absorbed & unabsorbed

How to plot the graph

Finding Ka from the slope

Advantages of this method

Clean & handwritten-style notes for easy remembering


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✔ Pharm D
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✔ YouTube study notes