Endoscopic Gastric Sleeve (ESG) Procedure Animation - apolloendo.com/esg

What is Endoscopic Sleeve Gastroplasty (ESG)?
ESG is an endoscopic weight loss procedure that has no scars and no incisions. A doctor sews the stomach into a smaller shape (sleeve) with a specialized device called the Apollo ESG™ System.
How is the ESG procedure performed?
While you are sleeping, a doctor who is specially trained passes a small camera and a suturing device through your mouth. After they reach the inside of your stomach, the doctor sews it into a smaller shape.
How does it help people lose weight?
The procedure makes the stomach approximately 70-80% smaller. You eat less food, so your system absorbs fewer calories. Food stays in the stomach longer, and you feel full longer.
How is ESG different from a laparoscopic gastric sleeve, gastric bypass, or other bariatric surgery?
Doctors perform ESG endoscopically, which leaves you with no incisions or scars. Most patients can go home the same day.
What are the most common side effects?
The most common side effects of ESG are gastrointestinal symptoms such as nausea, abdominal pain, vomiting, constipation, burping, or diarrhea. These symptoms typically resolve within 30-60 days. All procedures have risks. Patients should talk with their doctor and understand all risks before having any procedure.
Am I a candidate for this procedure? Apollo ESG™ is for adults with obesity (defined as having a Body Mass Index (BMI) between 30-50 kg/m2) who have not been able to lose weight or maintain weight loss through diet and exercise alone.
When can I return to work after ESG?
Patients typically return to work in 2-3 days.
How much weight can I lose with ESG?
According to a large, randomized clinical study1, patients lose an average of 14% of their body weight 12 months after undergoing the ESG procedure. Results will vary by person.
What are the potential positive health impacts of ESG?
ESG has not been specifically tested or FDA approved for the treatment of weight related health issues like diabetes or hypertension. However, in a clinical study1 that included some patients with diabetes and hypertension, most of the patients with those conditions lost weight. With the weight loss, they tended to show clinical improvement in those pre-existing conditions.

1 MERIT Study. The Lancet. 2022
Apollo ESG™ Safety Information for Patients
• Apollo ESG™ devices are made to help you lose weight by reducing the size of your stomach and increasing the time it takes for food to pass through your stomach.
• For Apollo ESG™ you need to follow a healthy diet and exercise program to lose weight. You may not lose weight if you do not adopt healthy habits. Your doctor’s
clinical team, including dieticians, nutritionists and/or exercise trainers, should help you on your weight loss journey.
• Apollo ESG™ System is for adults with obesity (BMI 30-50 kg/m2) who have not been able to lose weight and keep it off through more conservative measures (e.g.,
diet and exercise).
• Your doctor will ask you about your medical history and will also perform a physical examination to determine your eligibility for the Apollo ESG™ device. Additionally,
at the time of your procedure, the doctor may identify internal factors, such as stomach ulcers or erosive gastritis, which may prevent you from receiving the device.
• You must not receive Apollo ESG™ if you are pregnant.
• You must not receive Apollo ESG™ if you have an eating disorder (anorexia nervosa, binge eating disorder, etc.)
• All procedures have risk. Patients should talk to their doctor and understand all risks before having a procedure.
• Nausea and vomiting, abdominal pain, constipation, eructation, constipation, heartburn, and diarrhea are common after the ESG. Gastrointestinal bleeding may also be
experienced following these procedures. More serious complications have been reported, though these are relatively rare.
• While many patients are discharged from the hospital on the day of their procedure, some patients may stay in the hospital or return to the hospital for assistance with
symptoms associated with accommodating to the sleeve. Symptoms are most often treated with IV fluids or medication, but medical intervention may be required.
• Call your doctor if you have any concerns about your health or well-being following an ESG.
• Some patients may not lose weight following a procedure with Apollo ESG™. Others may lose weight and then report that they no longer feel full after a meal, like they
did when they first had their procedure. In such cases, the sleeve may have been compromised. Talk to your doctor about your options. You may be a candidate to have
the sleeve restored, reduced, or to have another type of weight loss procedure.
• If you have additional questions, talk with your doctor. For full safety information, visit apolloendo.com/dfu

CAUTION: Rx only. Individual Weight Loss May Vary
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