Скачать или смотреть Adrenergic Drugs | Chapter 18 - Pharmacology and the Nursing Process (10th Edition)

Chapter 18 of Pharmacology and the Nursing Process (10th Edition) explores adrenergic drugs, also known as sympathomimetics, which stimulate the sympathetic nervous system by acting on alpha, beta, and dopaminergic receptors. The chapter reviews endogenous catecholamines—epinephrine, norepinephrine, and dopamine—as well as synthetic agents such as dobutamine, phenylephrine, albuterol, and mirabegron. Adrenergic receptor subtypes (alpha1, alpha2, beta1, beta2, and beta3) are linked to physiologic responses such as vasoconstriction, bronchodilation, increased cardiac output, and bladder relaxation. Clinical uses span emergency resuscitation (epinephrine in cardiac arrest and anaphylaxis), bronchodilators for asthma and COPD, nasal decongestants, ophthalmic mydriatics, overactive bladder therapy, and vasoactive support in shock and heart failure. The chapter highlights direct-acting, indirect-acting, and mixed-acting mechanisms, as well as the short half-life of catecholamines. Nursing considerations emphasize monitoring for adverse effects like hypertension, dysrhythmias, tachycardia, tremors, and CNS overstimulation, along with careful IV administration to avoid extravasation. Patient education addresses safe inhaler use, avoiding OTC interactions, and recognizing toxicity. This chapter provides a comprehensive guide to adrenergic pharmacology in critical care, respiratory therapy, and cardiovascular emergencies.

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