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For the first time, optical coherence tomography (OCT) is being used to study the human inner ear directly in patients. In this follow-up conversation, Dr. John Oghalai, Professor and Chair of the Caruso Department of Otolaryngology at USC, shares the latest advances in this groundbreaking research.

Dr. Oghalai describes how his team has transitioned from animal studies to human imaging, uncovering new insights into conditions such as Meniere’s disease and vestibular schwannoma. By visualizing endolymphatic hydrops in real patients, this work moves closer to a future where handheld OCT devices could help audiologists and clinicians diagnose and monitor inner ear disorders in everyday practice.

The discussion explores both the promise and current challenges of developing practical, non-invasive imaging tools—technology that may one day transform care for hearing loss, tinnitus, and balance disorders.

Learn more about the work being conducted in Dr. Oghalai's lab: https://oghalailab.usc.edu/research/

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TIMESTAMPS
00:00 Introduction
02:04 Research background
03:22 Using Optical Coherence Tomography in the ear
07:43 Visualizing endolymphatic hydrops using OCT
12:09 Further developing technology for clinical use
15:53 Challenges of visualizing through ear canal
17:22 Potential future clinical applications
19:45 Developing the human OCT otoscope

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