Скачать или смотреть The Blood Brain Barrier's Impact on Brain Tumor Treatment

Riverside Neurosurgeon William McCallister IV, MD explains the blood brain barrier and its role in shaping cancer treatments for brain tumors and metastatic brain lesions. He explains that chemotherapy is not usually the first treatment option for brain tumors because of the blood-brain barrier—a protective layer of cells that protects the brain from harmful substances penetrating the brain tissue through the blood. While this barrier plays a vital role in maintaining brain during times of good health, it also blocks many chemotherapy drugs from reaching tumor cells as might be the case for other organs in the body. This limits the effectiveness of chemotherapy for brain tumors. For this reason, surgery and radiosurgery are the first options for brain tumors. Both directly target the tumor and are not hindered by the brain’s natural defenses.

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