Kongressupdate ESC II - ECLS-SHOCK & CAVA-ADHF - Prof. Dr. Holger Thiele

Prof. Dr. Holger Thiele - Direktor der Universitätsklinik für Kardiologie am Herzzentrum Leipzig der Universität Leipzig und Präsident der Deutschen Gesellschaft für Kardiologie - stellt die zentralen Ergebnisse seiner ECLS-SHOCK und CAVA-ADHF Studien vor. Beide Studien wurden beim Jahreskongress der European Society of Cardiology präsentiert; ECLS-SHOCK wurde parallel im New England Journal of Medicine publiziert.
ECLS-SHOCK untersuchte, ob Patienten kardiogenem Schock bei akutem Myokardinfarkt vom Einsat von ECLS ("Extracorporeal life support") ergänzend zur Standardtherapie profitieren.
CAVA-ADHF untersuchte die prognostische Bedeutung regelmäßiger Sonographien der Vena cava inferior bei Patienten mit akuter kardialer Dekompensation.

Das Gespräch wurde am 31.08.2023 geführt. Moderatoren: Prof. Dr. Dr. Christian Jung (Düsseldorf), Prof. Dr. Florian Custodis (Saarbrücken) und Prof. Dr. Gunnar Heine (Frankfurt am Main).

Weitere Literatur:

Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation.
Desch S, ..., Thiele H; TOMAHAWK Investigators.
N Engl J Med. 2021
doi: 10.1056/NEJMoa2101909.

Intraaortic balloon support for myocardial infarction with cardiogenic shock.
Thiele H, ...., Werdan K; IABP-SHOCK II Trial Investigators.
N Engl J Med. 2012
doi: 10.1056/NEJMoa1208410

Inferior vena cava ultrasound in acute decompensated heart failure: design rationale of the CAVA-ADHF-DZHK10 trial.
Jobs A, ...., Thiele H.
ESC Heart Fail. 2020
doi: 10.1002/ehf2.12598

One-Year Outcomes after PCI Strategies in Cardiogenic Shock.
Thiele H, et al.; CULPRIT-SHOCK Investigators.
N Engl J Med. 2018
doi: 10.1056/NEJMoa1808788

Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials.
Zeymer U, ..., Thiele H.
Lancet. 2023
doi: 10.1016/S0140-6736(23)01607-0

Extracorporeal Life Support in Infarct-Related Cardiogenic Shock.
Thiele H et al.
N Engl J Med 2023
doi: 10.1056/NEJMoa2307227

SCAI clinical expert consensus statement on the classification of cardiogenic shock: This document was endorsed by the American College of Cardiology (ACC), the American Heart Association (AHA), the Society of Critical Care Medicine (SCCM), and the Society of Thoracic Surgeons (STS) in April 2019.
Baran DA et al.
Catheter Cardiovasc Interv. 2019
doi: 10.1002/ccd.28329

SCAI SHOCK Stage Classification Expert Consensus Update: A Review and Incorporation of Validation Studies: This statement was endorsed by the American College of Cardiology (ACC), American College of Emergency Physicians (ACEP), American Heart Association (AHA), European Society of Cardiology (ESC) Association for Acute Cardiovascular Care (ACVC), International Society for Heart and Lung Transplantation (ISHLT), Society of Critical Care Medicine (SCCM), and Society of Thoracic Surgeons (STS) in December 2021.
Naidu SS et al.
J Am Coll Cardiol. 2022
doi: 10.1016/j.jacc.2022.01.018

Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial.
Patterson T et al.; ARREST trial collaborators.
Lancet. 2023
doi: 10.1016/S0140-6736(23)01351-X.

Oxygen Targets in Comatose Survivors of Cardiac Arrest.
Schmidt H et al.
N Engl J Med. 2022
doi: 10.1056/NEJMoa2208686

Natriuresis-guided diuretic therapy in acute heart failure: a pragmatic randomized trial.
Ter Maaten JM et al.
Nat Med. 2023
doi: 10.1038/s41591-023-02532-z

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest. Kjaergaard J et al.
N Engl J Med. 2022
doi: 10.1056/NEJMoa2208687

Diuretic strategies in patients with acute decompensated heart failure.
Felker GM et al.; NHLBI Heart Failure Clinical Research Network.
N Engl J Med. 2011
doi: 10.1056/NEJMoa1005419

Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography.
Rudski LG et al.
J Am Soc Echocardiogr. 2010
doi: 10.1016/j.echo.2010.05.010