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📘 Stereochemistry Lecture – 3 | Chirality, Optical Activity & CIP Rules Explained

🔹 In this 3rd Lecture of Stereochemistry, we will cover:

1️⃣ R–S Nomenclature in:
  • Fischer Projection → (Here the lowest priority group i.e. group 4 must be present on the vertical line)
  • Flying Wedge System → (Here the lowest priority group i.e. group 4 must be present on the dash)
  • Norbornane System

2️⃣ Detailed explanation of CIP (Cahn–Ingold–Prelog) Rules

3️⃣ Solving many questions based on R–S nomenclature and chirality concepts

4️⃣ Understanding the difference between chirality and chiral center

5️⃣ Does the presence of a chiral center always bring optical activity to the system?


🧠 Types of Chirality Discussed:

1️⃣ Central Chirality – seen in compounds having an asymmetric center or adamantane system
2️⃣ Axial Chirality – found in Allene, Biphenyl, Spiro, and Allene derivatives
3️⃣ Planar Chirality – seen in Ansa compounds, Paracyclophane, and Cyclooctene
4️⃣ Helical Chirality – discussed with suitable examples


🔬 Optical Activity Concepts:

🔹 Learn to check optical activity in Allene, Biphenyl, and Spiro compounds
🔹 Understand how proper substitution and presence of plane of symmetry (POS) affect optical activity
🔹 Discuss which symmetry elements affect optical activity – (Only POS and COS)


🎯 This video is perfect for:
👉 B.Sc., M.Sc., NET, GATE, IIT-JAM, CSIR-JRF, NEET, JEE, and +2 students
👉 Anyone aiming to build strong concepts in Chirality, Optical Activity, and Stereochemistry



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