Скачать или смотреть Time-lapse of a mouse brain being cleared with the X CLARITY™ Tissue Clearing System

A time-lapse video of a whole mouse brain clearing in just six (6!) hours using the X-CLARITY™ Tissue Clearing System from Logos Biosystems.

Supplementary Video 1 from: Lee, E. et al. ACT-PRESTO: Rapid and consistent tissue clearing and labeling method for 3-dimensional (3D) imaging. Sci Rep 6, 18631, 10.1038/srep18631 (2016). http://goo.gl/zqA9I7

Music: Air Hockey Saloon by Chris Zabriskie http://chriszabriskie.com/vendaface/

Edited to include text, images, and music.

The X-CLARITY™ Tissue Clearing System provides an all-in-one, easy-to-use solution for electrophoretic tissue clearing. The X-CLARITY™ combines unique electrodes and an active cooling system to accelerate the removal of lipids in a highly efficient manner. Lipid bilayers are broken up through electrophoresis in the presence of ionic detergents, leaving behind a stable and transparent tissue-hydrogel hybrid that is chemically accessible for molecular phenotyping.

The X-CLARITY™ dramatically reduces tissue clearing time and can clear a whole adult mouse brain in just 6-8 hours. The cleared tissues are efficiently penetrated and labeled with macromolecules such as antibodies or oligonucleotides.

Check out www.logosbio.com for more information.

The original video and music are licensed under a Creative Commons Attribution 4.0 International License.

2016