Hi, I’m Dr Praveen Kammar, Cancer Surgeon specializing in gastrointestinal and gynecological cancers
Today, I’m answering a question many rectal cancer patients ask: Can chemotherapy and radiation make the cancer disappear without surgery? Let’s break it down
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Video Flow
00:00 Introduction
00:13 Importance of preserving the rectum and lifestyle impact
00:59 Is non-surgical treatment possible
01:10 Total Neoadjuvant Therapy explained
01:54 Tumor disappearance rates with TNT
02:05 Avoiding surgery and stoma
02:18 Risks of recurrence and need for follow-up
02:48 Follow-up tests every 4 months
03:02 Long-term success in 50% patients
03:19 Final advice and patient responsibility
03:27 Conclusion
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क्या Chemoradiation से Rectal Cancer ठीक हो सकता है? | Rectal Cancer & Chemoradiation! | Dr Praveen
Why This Question Matters
Rectal cancer treatment isn’t just about survival. Patients often ask if they can avoid a permanent stoma or preserve their rectum. That’s a real concern. Even with successful treatment, side effects like altered bowel movements can affect lifestyle. So, the idea of avoiding surgery altogether sounds appealing — and yes, in some cases, it's possible
How Chemoradiation Can Work Without Surgery
The combination of chemotherapy and radiation has shown strong results in locally advanced rectal cancer. This method is called Total Neoadjuvant Therapy (TNT). In TNT, all chemo and radiation are given before surgery. In some patients, this leads to complete disappearance of the tumor
How Often Does the Tumor Disappear
Studies show that about 20% to 50% of patients undergoing TNT achieve a complete clinical response — meaning the tumor cannot be seen in scans or endoscopy. For those patients, we may choose a “wait and watch” approach instead of surgery
Why This Approach Matters
If the tumor disappears, patients might avoid surgery and its side effects. There’s a chance to preserve the rectum, maintain better bowel function, and skip a permanent stoma. But this approach only works in selected cases and must be monitored closely
Why Follow-Up is Critical
Just because the tumor disappears doesn't mean the cancer is gone forever. In some cases, it can come back months or even years later. That’s why we keep patients under intensive surveillance. Follow-up includes MRI and endoscopy every 4 months, especially in the first few years after TNT
What the Long-Term Data Shows
After 3 to 4 years of follow-up, data suggests that nearly 50% of patients who had a complete response stayed cancer-free and did not need surgery. That’s a major win for both survival and quality of life. But this only works when there’s strong clinical judgment and patient compliance
Rectal cancer can sometimes disappear after chemoradiation. But the key is choosing the right patients and following them up rigorously
If you or someone close to you is facing this decision, ask if TNT is suitable for your case. And always make sure a cancer surgeon is involved early in the decision-making. That single step can change the outcome entirely
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About Dr. Praveen Kammar
Dr Praveen Kammar is a surgical oncologist practising in the city of Mumbai.
He completed his MCh course in surgical oncology from the reputed Tata Memorial Centre, Mumbai, one of the premier cancer care centres in the country. He also holds a fellowship in Colorectal surgery from Yopnsei cancer centre, Seoul, South Korea. Dr Praveen’s main area of focus is colorectal and GI oncology, Gynecological cancers, minimal access surgeries for abdominal and thoracic malignancies, transanal surgeries, and sphincter-saving surgeries for rectal cancer, cytoreductive surgeries, and HIPEC for advanced abdominal cancers.
#RectalCancer #CancerTreatment #Cancer #ColorectalCancer #Chemoradiation #CancerSpecialist #ColonCancer #Chemotherapy #Radiation #DrPraveenKammar
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