How do GnRH analogues work? Zoladex, Prostap and other GnRH analogues

A simple explanation of how GnRH analogues like goserelin (Zoladex) and Leuprorelin (Prostap) work to induce a medical menopause or medical castration to treat conditions like endometriosis and prostate cancer. This includes a basic explanation of the hypothalamic-pituitary-gonadal axis in men and women.

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