Dr. John Tsang presents a systems-level framework for understanding the human immune system as a predictive, quantifiable biological network. Introducing the concept of immune set points—stable baseline immune states—this talk demonstrates how individual immune profiles shape vaccine responses, disease susceptibility, autoimmune flares, cancer immunotherapy outcomes, and long-term health trajectories. Integrating multi-omic data, single-cell profiling, AI modeling, and systems biology, the work establishes foundations for immune digital twins, immune health metrics, and the Human Immunome Project—an international effort to map human immune variation across populations and environments.
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