Extractive Value | Determination of Water Soluble Extractive Value of Crude Drugs | HINDI

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EXTRACTIVE VALUE
Water-soluble extractive value plays an important role in the evaluation of crude drugs. The less extractive value indicates the addition of exhausted material, adulteration, or incorrect processing during drying or storage or formulating. Extractive value is of two types- water-soluble and alcohol soluble that depends on the solvent used. if the water is used as a solvent it will be known as water-soluble extractive value and if alcohol is used in the place of water than it will know as alcohol soluble extractive value.

Determination of Extractive values
These are useful for the evaluation of a crude drug. Gives an idea about the nature of the chemical constituents present in the crude drug. Useful for the estimation of constituents extracted with the solvent used for extraction. Employed for material for which as yet no suitable chemical or biological assay exists.

Preparations of the extracts
Cold Maceration
1. Macerate 5g of the powdered crude drug with 100 ml of solvent in a closed flask for 24 hours, shaking frequently during the first 6 hours and allowing to stand for 18 hours. 2. Filter rapidly taking precaution against loss of solvent, evaporate 25ml of the filtrate to dryness in an evaporating dish to avoid the decomposition of natural metabolites, dry at 105 degrees C, and weigh.
3. Calculate the percentage of water, alcohol, chloroform and petroleum ether soluble extractive value with reference to the air-dried drug.

Importance of Extractive values: -
Extractive values are primarily useful for the determination of exhausted or adulterated drugs. The extractive value of the crude drug determines the quality as well as the purity of the drug. Thus, alcohol and water-soluble extractive values were determined.

After watching this video you will be able to answer- what is extractive value, the importance of extractive value, what is extraction, how to extract plant part, the importance of extraction value, how to determine extraction value,

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