Скачать или смотреть Doripenem; Chemical name, Molecular Formula, Molar mass, Chemical Structure

Doripenem is a carbapenem-class β-lactam antibiotic with the molecular formula C₁₅H₂₄N₄O₆S₂, a molar mass of 420.51 g/mol, and a bicyclic β-lactam structure featuring a thiazole ring and sulfonamide substituents. It is used for serious infections such as complicated intra-abdominal infections, urinary tract infections, and hospital-acquired pneumonia.

🔬 Doripenem Key Chemical Information
Chemical name (IUPAC):
(4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-sulfamoylpyrrolidin-3-yl]thio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Molecular formula:
C₁₅H₂₄N₄O₆S₂

Molar mass:
420.51 g/mol

Chemical structure:

Built on the carbapenem nucleus (β-lactam fused to a five-membered ring).

Contains a hydroxyethyl group at position 6.

A sulfamoylpyrrolidinyl substituent attached via a thioether linkage.

Multiple carbonyl (-C=O) and hydroxyl (-OH) groups contribute to polarity and activity.

The β-lactam ring is essential for antibacterial action, inhibiting cell wall synthesis.

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