Cell Migration - Amrita University

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Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing and immune responses all require the orchestrated movement of cells in particular directions to specific locations.

Directed cell migration accompanies us from conception to death. The failure of cells to migrate or migration of cells to inappropriate locations can result in life threatening consequences such as the congenital defects prominent in the brain. In the adult, cell migration is central to homeostatic processes such as mounting an effective immune response and the repair of injured tissues.It contributes to pathologies including vascular disease, chronic inflammatory diseases, and tumor formation and metastasis. Understanding cell migration is also becoming important to emerging areas of biotechnology which focus on cellular transplantation and the manufacture of artificial tissues.