Скачать или смотреть Septic Shock Causes, Symptoms and Prevention

Septic Shock is a life-threatening condition that happens when a severe infection leads to dangerously low blood pressure and organ dysfunction. It is the most severe form of sepsis.


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🔹 Causes

Severe bacterial, viral, or fungal infection

Common sources:

Pneumonia (lungs)

Urinary tract infection (kidneys, bladder)

Abdominal infections (appendicitis, peritonitis)

Skin or wound infections

Bloodstream infections




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🔹 Pathophysiology (simplified)

1. Infection → immune system overreacts


2. Release of inflammatory chemicals (cytokine storm)


3. Widespread vasodilation + leaky blood vessels → drop in blood pressure


4. Poor oxygen supply to organs → organ failure




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🔹 Symptoms

Persistent low blood pressure (even after fluids)

Fever, chills, or very low body temperature

Rapid heart rate (tachycardia)

Rapid breathing, shortness of breath

Confusion or altered mental state

Cold, clammy skin or mottling

Decreased urine output



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🔹 Diagnosis

Blood tests (lactate, cultures, inflammatory markers)

Low blood pressure not responding to fluids

Signs of organ dysfunction (kidneys, liver, heart, brain)



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🔹 Treatment (Emergency)

Immediate hospital/ICU care

IV antibiotics (broad-spectrum, then tailored)

IV fluids to raise blood pressure

Vasopressors (e.g., norepinephrine) if fluids aren’t enough

Oxygen or mechanical ventilation if needed

Source control (e.g., drain abscess, remove infected device)



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🔹 Prevention

Early treatment of infections

Good hygiene and wound care

Vaccinations (for pneumonia, flu, etc.)

Careful infection control in hospitals