pH, pKa, and Retention

Описание к видео pH, pKa, and Retention

When it comes to Ionizable compounds such as acid or base, their retention time can vary based on their ionization extent.

How do the pH and pKa influence retention?

What is the best pH for acidic or basic compounds?

I have designed a spreadsheet to define the retention of a polar compound as per the pH of the mobile phase.

Fill out this form and get a copy of it thru an email: https://forms.gle/Afqp46DwkRUcBNeKA

#pKa #pH #HPLC #MethodDevelopment #PharmaGrowthHub #analyticalchemistry

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