Скачать или смотреть BactoGeNIE: Scalable Genome Visualization For Large, High Resolution Environments

This video demonstrates BactoGeNIE, the Bacterial Gene Neighborhood Investigation Environment, a genome visualization approach to address growing volumes of genome sequence data, specifically microbial genomes, in the biological sciences. Decreases in sequencing costs have driven a proliferation in the volume of complete sequenced genomes. Existing visualization approaches are not designed to enable the comparison of hundreds to thousands of sequenced genomes in one view. At the same time, advances in display hardware have enabled growth in display resolution and the development of large, high-resolution display environments, presenting an opportunity for high-resolution visualization design.

In this video, we present a novel high-resolution genomics visualization approach that transforms genomics data into high-resolution digital genomic maps that enable rapid comparison of hundreds of genomes in one view. The video shows segments of the 600 draft E. coli genomes from the PubMed database displayed on the Cyber-Commons display wall at the University of Illinois at Chicago, Electronic Visualization Laboratory. Alignment of similar genes from related bacterial strains and coloring by gene identity on a gradient around a target gene, enables researchers to quickly spot insertion, inversion and deletion events across hundreds of bacterial strains. BactoGeNIE demonstrates the potential of high-resolution display environments to facilitate large-scale genomic data analysis.