Introduction to Dovetail™ Micro C Technology

The Dovetail Micro-C Kit enables capture of chromatin topology at a mono-nucleosome resolution. The proximity ligation workflow uses micrococcal nuclease (MNase) for even and highly reproducible chromatin fragmentation with the following benefits:
1. Highest resolution achievable – Capture topological features down to mono-nucleosome positioning
2. Less cost per sample – Create high resolution contacts maps with lower sequencing depth
3. Uniform sequence coverage – no restriction site coverage biases due to use of a sequence-independent MNase enzyme
Dovetail Micro-C Technology represents the next evolution to Hi-C for high-resolution mapping of chromatin topological features.



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Dovetail Genomics is a Santa Cruz­‐based start­up life sciences company developing cutting­‐edge genomics technologies for vastly improving genome assembly, uncovering critical structural variation information, and many other exciting applications in genomics.

Website: www.dovetailgenomics.com
Email: [email protected]
Twitter: @DTGenomics
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