Mechanism of enzyme action | Lock And Key Model | Class 11 Biology

Описание к видео Mechanism of enzyme action | Lock And Key Model | Class 11 Biology

Mechanism of enzyme action | Lock And Key Model | Class 11 Biology

About This Video ........................
In This Video Lecture You Will Learn Basic Concept of
Mechanism of enzyme action
An enzyme is a three dimensional globular protein that has specific chemical composition due to
its component amino acids and a specific shape. Every enzyme by virtue of its specificity recognizes
and reacts with a special chemical substance called substrate. Any enzyme, therefore, reacts only
with its specific substrate and transforms it into product(s). It is then released unaltered and thus
can be used again and again.
An enzyme and its substrate react with each other through a definite charge-bearing site of an
closer and are arranged in a specific way by coiling and folding of the polypeptide chain within the
present in the polypeptide chain of the active site of the enzyme. These amino acids are brought
enzyme called active site. The charge and shape of the active site is formed by some amino acids
globular symmetry of the enzyme
The active site of the enzyme is made up of two definite regions i.e the binding site and the catalytic
to this model, as one specific key can open only a site. The binding site helps the enzyme in the recognition and binding of a proper substrate to in specific and orderly arrangements. visualize substrate and enzyme interaction. According
specific lock, in the same manner a specific enzyme can
the transformation of the substrate into product(s). Thus the enzyme after catalysis detaches itself
flexibility in the active site before, during or after the enzyme action and it is used only as a template.
transform only one substrate into products(s).to membrane systems inside the cell Most enzymes do not float about in a kind from the products unchanged. Enzyme requires aqueous medium for its activity.
According to Lock and Key Model the active site is a rigid structure. There is no modification or
produce an ES complex. This reaction activates the catalytic site. Activated catalytic site catalyzes examples of this.
Mitochondria and chloroplasts are good Emil Fischer (1890) proposed a Lock and Key model to
of cytoplasmic soup’ but are attached Later studies did not support this model in all reactions.

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