Ibuprofen 400 vs. 800mg - GLEICHE Wirkung?

Bedeutet doppelte Menge Wirkstoff auch doppelt gute Wirkung gegen Schmerzen? Spoiler: Nee!

Was ist mit Nebenwirkungen?

Wann Ibu 400 mg, wann Ibu 800 mg?

Erklärt euch die 400 er Variante im Video 😉

Quellen:

Bradley, J. D., Brandt, K. D., Katz, B. P., Kalasinski, L. A., & Ryan, S. I. (1991). Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. The New England Journal of Medicine, 325(2), 87–91. https://doi.org/10.1056/NEJM199107113...

Klauer, K. M. (2019). Myths in EM: The Anti-Inflammatory Properties of NSAIDs. ACEP Now. https://www.acepnow.com/article/myths...

Lyngstad, G., Skjelbred, P., Swanson, D. M., & Skoglund, L. A. (2021). Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study. European Journal of Clinical Pharmacology, 77(12), 1843–1852. https://doi.org/10.1007/s00228-021-03...

Motov, S., Masoudi, A., Drapkin, J., Sotomayor, C., Kim, S., Butt, M., Likourezos, A., Fassassi, C., Hossain, R., Brady, J., Rothberger, N., Flom, P., & Marshall, J. (2019). Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial. Annals of Emergency Medicine, 74(4), 530–537. https://doi.org/10.1016/j.annemergmed..."