Скачать или смотреть Quality Control of Proteins in Endoplasmic Reticulum (ER) | Protein Folding, Chaperones & ERAD .

Quality Control of Proteins in the Endoplasmic Reticulum (ER) is a crucial cellular process that ensures only properly folded and functional proteins are transported to their destination.

Inside the ER, newly synthesized proteins are checked by molecular chaperones such as BiP, calnexin, and calreticulin. If proteins are misfolded or unfolded, they are either refolded or sent for degradation through the ER-Associated Degradation (ERAD) pathway.

This quality control system prevents the accumulation of defective proteins and protects cells from ER stress, which is linked to diseases like neurodegeneration, diabetes, and cancer.

📚 Very important topic for:
✔ Cell Biology
✔ Molecular Biology
✔ CSIR NET / GATE / PhD Interviews
✔ Biomedical Research

👉 Watch till the end to understand protein folding, ER stress, and degradation in the simplest way!
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