Biochemical Functions of Albumin || Clinical Significance of Albumin || Plasma Proteins

This is the video on biochemical functions of albumin and it's clinical significance with NEET PG MCQs and example of theory questions.
00:00 - Introduction
00:29 - Examples of theory questions
00:45 - Plasma Proteins
01:37 - Albumin
03:11 - Functions of Albumin
03:20 - Osmotic function of albumin
04:09 - Starling Hypothesis of albumin
05:27 - Transport functions of albumin
06:14 - Nutritive functions of albumin
06:56 - Buffering function of albumin
07:29 - Normal ranges and method for estimation
07:54 - Clinical Significance of Albumin
08:16 - Hypoalbuminemia
08:43 - Causes of Hypoalbuminemia
11:12 - Hyperalbuminemia
11:35 - Analbuminemia
12:09 - Albumin and Blood brain barrier
12:50 - Albumin and drug interactions
13:20 - Protein bound calcium
14:08 - NEET PG MCQs


The name is derived from the white precipitate when egg is boiled (Latin=albus=white)
It constitutes the major part of plasma proteins(58%).
It has one polypeptide chain with 585 amino acids with 17 disulfide bonds.
It has a molecular weight of 69000 D.
It simple globular protein with isoelctric pH around 4.7

Biochemical Functions of Albumin
1. Osmotic function
2. Transport function
3. Nutritive function
4. Buffering function

Clinical Significance of Albumin
Serum Albumin measurements are used to assess the various clinical conditions: e.g:
Hypoalbuminemia
Hyperalbuminemia and
Analbuminemia


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