Pharmaceutical organic chemistry 3rd semester important questions । Short & long Questions। Part-1।

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Today In this video I provide Pharmaceutical organic chemistry-2 (POC-2) B Pharm 3rd semester important questions : Short & long questions with solution pdf. (Part-1)



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Unit-I
Benzene and its derivatives
A. Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital
picture, resonance in benzene, aromatic characters, Huckel’s rule.
B. Reactions of benzene - nitration, sulphonation, halogenation- reactivity, Friedel Crafts alkylation-reactivity, limitations, Friedel Crafts acylation.
C. Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction.
D. Structure and uses of DDT, Saccharin, BHC and Chloramine T.

Unit-II
Phenols - Acidity of phenols, effect of substituents on acidity, qualitative tests,
Structure and uses of phenol, cresols, resorcinol, naphthols.
Aromatic Amines* - Basicity of amines, effect of substituents on basicity, and synthetic
uses of aryl diazonium salts.
Aromatic Acids*– Acidity, effect of substituents on acidity and important reactions of benzoic acid.

Unit-III
Fats and Oils: Fatty acids – reactions.
Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils.
Analytical constants– Acid value, Saponification value, Ester value, Iodine value, Acetyl value, Reichert Meissl (RM) value– significance and principle involved in their
determination.

Unit-IV
Polynuclear Hydrocarbons: Synthesis, reactions.
Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives.

Unit-V
Cycloalkanes
Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only.