What's Urolithin A and can it stimulate mitophagy and increase muscle endurance?

The naturally-occurring antiaging compound that improves mitochondrial and muscle function giving you faster recovery and more energy.

Urolithin A is produced by bacteria in the gut microbiome, making it a postbiotic. It is synthesised after eating certain foods that are high in ellagitannins, part of a family of bioactive polyphenols found in berries, nuts and most famously, pomegranates.

There's a lot to be said for healthy eating and ensuring a varied diet that benefits from as many advantageous compounds as possible. However, simply loading up your shopping cart with pomegranates won't automatically confer the benefits of urolithin A on you; your gut needs to have the correct microbiome environment to be able to make sufficient quantities of urolithin A, and not everyone can do that.

Specifically, people who have more bacteria from the Clostridiales and Ruminococcaceae families living in their gut can produce urolithin A (these people are often termed "producers"). In fact, few as 1 in 3 people produce enough urolithin A! The only way to ensure you are getting enough urolithin A is from direct supplementation.

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