Classification of Adrenergic Drugs || Individual Adrenergic Drugs || Sympathomimetics Pharmacology

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Classification of Adrenergic Drugs
Classification of adrenergic drugs includes endogenous catecholamines, drugs that act directly on the receptors, indirectly acting drugs, and mixed-acting sympathomimetics. Endogenous catecholamines are epinephrine, norepinephrine, and dopamine. Selective α1 agonists are phenylephrine, methoxamine, and midodrine. Selective α2 agonists are clonidine, methyldopa, guanfacine, guanabenz, moxonidine, rilmenidine, dexmedetomidine, tizanidine, naphazoline, xylometazoline, oxymetazoline, apraclonidine, and brimonidine. Isoproterenol is a nonselective β agonist. Dobutamine is β1 subtype-selective agonist. Selective β2 agonists are salbutamol, terbutaline, salmeterol, formoterol, ritodrine and isoxuprine. Amphetamine-like drugs, which increase transmitter release are amphetamine, methamphetamine, methylphenidate, modafinil, and tyramine. Catecholamine reuptake inhibitors are imipramine, amitriptyline, sibutramine, duloxetine, milnacipran, atomoxetine, and cocaine. Mixed actin sympathomimetic drugs are ephedrine, mephentermine, and pseudoephedrine.

Dr Vipul Navadiya

Chapters:
00:00 Introduction
01:21 Endogenous Catecholamines
05:40 Direct Acting Sympathomimetics
12:13 Indirect Acting Sympathomimetics
16:51 Mixed Acting Sympathomimetics
17:55 Summary

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