Dutasteride VS Finasteride - Which Is BETTER For Your Hair Growth?

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Dutasteride or finasteride? Which is better? We have a detailed, point by point comparison coming right up. And in the end, we’re gonna give you our verdict. There is a winner, and you’ll find out who it is in today’s video.

Timestamps:
📌0:00 - Intro
📌1:05 - Mechanism of action
📌2:46 - Efficacy
📌4:42 - Side effects
📌6:02 - Price
📌6:35 - Availability
📌7:14 - Popularity
📌7:40 - The overall winner

Transcription:

Today we’ll be comparing finasteride to dutasteride across various domains, like their efficacy and side effects.

We’ll give you the winner in each area.

And in the end we’ll give you our verdict on the overall winner.

So let’s get into it.

Mechanism of action.

So both finasteride and dutasteride block DHT.

And they do this in a similar way: by inhibiting the enzyme that converts testosterone into DHT.

This enzyme is called five-alpha-reductase.

By inhibiting this enzyme, our body is unable to convert the circulating testosterone into DHT, and the levels of DHT drop.

Dramatically.

So both drugs are so-called 5-alpha-reductase inhibitors.

But there is a big difference between them.

There are versions of the 5-alpha-reductase enzyme.

These are simply called type 1 and type 2. They have a slightly different chemical structure but exactly the same function: they both convert testosterone to DHT.

Now finasteride only inhibits the type 2 enzyme.

Whereas dutasteride inhibits the type 1 and type 2.

And because our body makes DHT from both enzymes, dutasteride results in a near-total suppression of DHT levels, over 90%.

This compares to around 70% reduction from finasteride.

So, clearly, the winner here is dutasteride, right?

Well, actually no.

You see, it’s only the DHT made from the type 2 enzyme that causes hair loss.

We know this from a rare genetic mutation that makes some people lack a functional type 2 enzyme.

These people still have DHT in their system from the type 1 enzyme, but they’re immune to hair loss.

So even though dutasteride is the most efficient DHT blocker of the two, you judge a medication by its selectiveness, not by its potency.

If it’s only the type 2 enzyme that causes hair loss, the superior medication is the one that only blocks the type 2 enzyme, not both.

The more targeted the medication, and the less it interferes with other aspects of our biochemistry, the better.

WINNER: FINASTERIDE

Efficacy

So both drugs are efficient at blocking the progression of hair loss, at least for the majority of users.

There is so much research at this point that this is beyond doubt.

But which of the two is better? With which one are you more likely to regrow hair?

Now guys I want to be clear: the differences between the two drugs aren’t that large.

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Reference Links:
https://www.ncbi.nlm.nih.gov/pmc/arti...
https://onlinelibrary.wiley.com/doi/p...
https://www.sciencedirect.com/science...
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   • Finasteride FAQs (Dosage, Costs, and ...  

Disclaimer
This video is for educational purposes only and is not intended to treat, diagnose or cure any disease.