Bleeding Disorders and Drugs Explained

Bleeding disorders and anticoagulant drugs are critical topics to understand in surgery!

Today we're going to make learning bleeding disorders such as hemophilia and drugs such warfarin easy...you're goin to be a pro and crush the exams!


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Sabiston's Textbook of Surgery https://citizensurgeon.co/Sabiston
Moore's Clinically Oriented Anatomy https://citizensurgeon.co/Moore
Netter's Anatomical Atlas https://citizensurgeon.co/Netter
Schwartz Principles of Surgery https://citizensurgeon.co/Schwartz
Fischer's Mastery of Surgery https://citizensurgeon.co/Mastery
Zollinger's Atlas of Surgical Operations https://citizensurgeon.co/Zollinger
Top Knife (MUST MUST HAVE) https://citizensurgeon.co/topknife


Hopefully you have finished the first video on bleeding and hemostasis, if you haven't I strongly recommend you check out the video here: http://citizensurgeon.co/bleeding

Ok, awesome! Now that you've watched that video on the foundation of bleeding you're ready to take on this video and learn all of the bleeding disorders and anticoagulants!

We're going to cover many of the most important bleeding disorders and drugs including antiplatelet and anticoagulant agents. We're going to do a few things in this video and after it I know you're going to feel like you can crush all of those MCQs on this difficult subject and be confident on the wards, in the OR and in the ICU.

If you want to fast forward you can with these totally amazing timestamps!

Start 00:00
Why know bleeding disorders? 01:26
Goals for Today's Talk 02:32
When to worry about bleeding 03:37
Diagnostic tests for bleeding 04:53
Reviewing Hemostasis 05:53
Inhibitors of Platelet Aggregation 07:03
Modulating Primary Hemostasis 08:30
Common Diseases of Primary Hemostasis 09:08
Targeting the Coagulation Cascade 12:51
Warfarin (Coumadin) Mechanism and Action 13:56
Heparin Mechanism and Action 18:06
Lovenox Mechanism and Action 20:11
Fondaparinux - How it works? 20:55
Hemophilia A - How to diagnose and treat 22:11
Hemophilia B - The Other Hemophilia 23:10
Liver Disease and Coagulopathy 23:38
VItamin K deficiency and the coagulation cascades 24:32
Fibrinolysis 25:05
Disseminated Intravascular Coagulation 25:48
A Big Important Table 27:10

Here are the goals:

1.). Review the mechanisms of primary hemostasis, fibrin formation and fibrinolysis. (A brief brief review of the first video)

2.). Understand the antiplatelet agents including drug targets and therapy

3.). Know the diseases associated with primary hemostasis including Glanzmann's Thrombasthenia and Bernard-Soulier Syndrome.

4.). Evaluate all of common anticoagulants including Vitamin K antagonists, Heparin, Low Molecular Weight Heparin and Fondaparinux.

5.). Know the common bleeding diatheses including Hemophilia A, B and Liver disease

6.). Understand fibrinolysis and DIC including it's triggers and pathogenesis.

SOME RECENT READS
The Miracle Morning by Hal Elrod - http://citizensurgeon.co/MiracleMorning
Atomic Habits by James Clear - http://citizensurgeon.co/AtomicHabits

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WHO AM I?
I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a weekly newsletter called the Saturday Six where I identify Six different discoveries of the week. You can get the weekly newsletter by signing up to the CITIZENSURGEON Community!

DISCLAIMER
While my aim is to help educate you for the ward, the surgical ICU, the operating room and your exams remember these videos are not a replacement for your reading, your medical school and residency preparation and most important your own decision making. Good luck and enjoy!

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