Inflammation and the Metabolic Response to Injury

What is the metabolic response to injury and trauma? How does the body respond to pain?

What cascades are initiated by hypovolemia and hemorrhagic shock?

What about all of those circulating hormones and cytokines following injury?

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Welcome back friends! In this tutorial we'll take a deep dive into the Metabolic Response to Injury and Trauma. It's a difficult topic and this is a pretty long video so I've provided some shortcuts below!

WHAT YOU ARE GOING TO LEARN
1.). The THREE major factors involved in the body's metabolic response to injury
2.). The hormones critical in the injury response
3.). The most important cytokines involved in injury and their function

FAST FORWARD WITH THESE TIMESTAMPS

Start 00:00
Goals for Understanding 01:14
Why are we learning about the Metabolic Response to Injury 02:00
What are the 3 Major Stimulants of the Body's Response to Injury 02:40
Pain, Fear and Anxiety and Related Hormones 03:11
Hypovolemia, Baroreceptors and Feedback Loops 05:20
Circulating Hormones, Cytokines and Interleukins 08:05
An Awesome Table for Hormones 08:37
Autonomic Nervous System and the Body's Response to Injury 13:32
RAA Axis, Glucagon and Insulin 15:49
Another Awesome Table for Cytokines 18:21
Summary and Tying it All Together 21:02

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WHO AM I?
I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a weekly newsletter called the Saturday Six where I identify Six different discoveries of the week. You can get the weekly newsletter by signing up to the CITIZENSURGEON Community!

REFERENCES
Norton's General Surgery Textbook - http://citizensurgeon.co/Norton

DISCLAIMER
While my aim is to help educate you for the ward, the surgical ICU, the operating room and your exams remember these videos are not a replacement for your reading, your medical school and residency preparation and most important your own decision making. Good luck and enjoy!

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