Telomere DNA Replication - Chromosome end replication problem in eukaryotes

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In this deep-dive video we discuss the DNA replication of telomeres, which are novelties for linear chromosomes, especially the eukaryotes. We understand the telomere structure, telomerase enzyme, and delve into the end replication problem. I focus on both leading strand and lagging strand DNA replication to ensure you get a complete understanding of the telomere replication issue. Throughout the video, we also make sure to discuss the entire process in context of various telomere-associated proteins, especially the Shelterin complex.

Jump to your favorite section:
00:00 Outline
00:34 Telomere structure
04:07 Telomerase enzyme
07:05 End replication problem
08:12 Leading Strand telomere
11:20 Lagging Strand telomere

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