Is DHT the ONLY cause of male pattern baldness ? | What is the DHT Paradox?

Is DHT the only cause of baldness?-Well, evidence suggests that DHT may not be the only cause of male pattern baldness!
Questions & Skepticism abound regarding the exact role of DHT.
In this video I discuss the many Paradoxes of Male Pattern Alopecia and of the role of DHT in causing androgenetic alopecia.
Male pattern baldness or androgenetic alopecia besides being a scourge for male vanity, is often an insurmountable challenge to the treating surgeon. Despite this and after decades of research we still do not know all about why some people get bald and others do not!
Once affected by male pattern baldness, hair follicles begin to shrink with each passing cycle. This miniaturization, or conversion of terminal hairs to vellus, and reduction of anagen to telogen ratio leads to excessive hair loss and in time balding. Eventually bald areas appear which slowly become slick bald and then progress to cover larger areas which outstrip availability of donor grafts.
Despite the fact that its prevalence is 80% of men and 50% of women throughout a lifetime, and that it has been extensively studied and researched over many decades, we have still not built a coherent pathology model that would logically and scientifically prove its precursors, biological step-processes, and physiological responses.
Though theories about male pattern baldness and counter arguments of pathophysiology abound, these 4 facts are unchallenged:
• 5-alpha reductase enzyme activity increases in the scalp of the patient with androgenetic alopecia. Males with a genetic deficiency of 5-αR2 never develop baldness
• Increased levels of DHT are detected in the scalp
• There is an increase in DHT receptors in the scalp
• Inhibiting the conversion of testosterone to DHT helps in reigning in androgenetic alopecia
Consensus supports a genetic, and androgen-mediated causation mechanism as responsible for male pattern baldness. It is today widely accepted that DHT, which is the strongest form of the androgen testosterone is the reason for miniaturization or shrinkage of hair follicles in male pattern baldness.
But this Theory is riddled with valid counter-arguments and abound.
Those who support this Genetic Theory that hovers around the primary role of DHT, can help answering these 7 questions that continue to confound:
1. What causes DHT to increase in tissues prone to baldness?
2. How does DHT miniaturize baldness-prone hair follicles?
3. Why is DHT also responsible for hair growth as part of the development of secondary sexual characteristics in males?
4. Pre-pubertal castrates undergo a permanent 95% reduction in endogenous androgen production and never develop male pattern baldness later in life. But why does castration not reverse male pattern baldness in post-pubertal castrates. Why does it merely stop it’s progression?
5. Is there a correlation between DHT and tissue remodeling that goes hand in hand alongside onset of male pattern baldness?
6. Why do identical twins have dissimilar balding patterns and speed of baldness. Does epigenetics also play a role?
7. If the incidence of baldness increases with aging, how do you explain this in the setting of lower androgen production in this age group?
_____________________________________________
Watch more about male pattern baldness at:

------------------------------------------------------------------------
Know the World's TOP 25 hair transplant surgeons:
   • Top 25 Hair Transplant Doctors for 20...  
https://www.apetogentleman.com/worlds...
_______________________
OUR CLINIC (SAFETY FIRST):
https://darlingbuds.com/doctor-profile
_______________________
FOLLOW ME!
Come and follow me on...
Facebook:  / darlingbudsclinic  
Twitter:   / tejinderbhatti  
LinkedIn:   / darlingbudsclinic  
Check out my blog too: https://darlingbuds.com/blog
________________________
COMMENT | SHARE | SUBSCRIBE
This is Dr Bhatti's Darling Buds Clinic. Our YouTube channel is a destination for those researching Hair Transplant and other remedies for hair loss. We make videos to showcase our hair transplant results on the web through YouTube; all techniques available for hair transplant; and advances in the field of hair transplant are often dealt with.
________________________
PRODUCTION CREDITS
All videos are shot, edited and uploaded by the Darling Buds Team
________________________
This video is not sponsored. All our videos are non-profit in nature and meant to educate, inform and empower hair loss sufferers around the world. Know more about us at-    / dearbhatti  
________________________
If you have any questions or want more information while you do your research before your procedure, e-mail us at: [email protected]
Call or whatsapp us at: +919814531111

#DHT #androgeneticalopecia #darlingbudsclinic