How Does Microbiome Affect Metabolism and Body Weight? | Will Bulsiewicz | The Proof Podcast EP

Dr Will Bulsiewicz is an absolute powerhouse when it comes to the science of gut health and the microbiome. He’s also a favourite on The Proof, dating back to his ground-breaking first appearance on Episode #17 of the show.

👇 Visit The Proof website for the full show notes and supporting studies. 👇

https://theproof.com/podcast/

Having returned to The Proof multiple times since that initial episode, Dr Bulsiewicz has joined me to explore various topics, including building the foundations of a healthy gut, why people quit plant-based diets, and most recently, how to heal your microbiome after antibiotics. In Episode #275, we shift our focus to how the microbiome affects metabolism.

Known as “Dr B”, Dr Will Bulsiewicz is a renowned gastroenterologist and a leading authority on gut health on the international stage. He is the author of the New York Times bestsellers Fiber Fueled and The Fiber Fueled Cookbook and has been honoured with awards in his field. In addition to serving as the US Medical Director and being a member of the Scientific Advisory Board for ZOE, a personalised nutrition company, Dr Bulsiewicz has contributed to over twenty peer-reviewed scientific journals. He has presented more than forty times at national meetings, presented to Congress and the USDA, and helped educate and guide more than 10,000 students on their journey to achieve optimal gut health.

In today’s conversation, we zoom in on the three ways that the microbiome affects our metabolism: through energy balance, blood glucose control (insulin resistance), and blood lipids.

Specifically, we cover:
00:00 Intro
2:42 - Introduction to Dr. Will Bulsiewicz and His Literary Contributions
9:55 - Dr. Will Bulsiewicz's Collaboration with ZOE
11:20 - Behind the Scenes: Dr. Will's Nutritional Supplement Venture
14:02 - The Progressive Journey of the Gut Health Movement
17:20 - Decoding the Microbiome: Its Role and Significance in Health
24:50 - Exploring Metabolism and Metabolic Health
33:32 - The Microbiome's Role in Influencing Metabolism
39:21 - Understanding GLP-1 Agonists: Their Impact on Satiety and Weight Reduction
45:30 - Tips to Increase Dietary Fibre Intake for Better Health
48:00 - The Connection Between Microbiome and Fat Metabolism
51:58 - The Role of Lipopolysaccharide in Gut Barrier Functionality
55:15 - Significance of Gut Health and the Risks of Dysbiosis
56:40 - Linking Insulin Resistance with Satiety Mechanisms
1:02:30 - Analysing Kevin Hall's Research: Plant-Based Diet vs. Alternative Diets
1:11:30 - Blood Regulation, Insulin Resistance, Lipotoxicity, and Microbiome
1:22:44 - The Interplay Between Insulin Resistance and Obesity Factors
1:24:11 - The Beneficial Role of Dietary Fibre in Blood Sugar Management
1:26:10 - Is Reversing Type 2 Diabetes a Possibility?
1:33:05 - How the Microbiome Influences Blood Sugar Regulation Mechanisms
1:37:58 - The Cholesterol-Lowering Benefits of Dietary Fibre
1:40:30 - Top Sources of Soluble Fibre for a Healthy Diet
1:43:00 - Triglycerides and Their Relationship with the Microbiome
1:47:21 - The Protective Role of Fibre in Disease Prevention
1:52:35 - Outro

Connect with Dr Will Bulsiewicz:
- Instagram:   / theguthealthmd  
- Facebook:   / theguthealthmd  
- Twitter:   / theguthealthmd  
- TikTok:   / theguthealthmd_  
- Website: https://theplantfedgut.com/
- Supplement: https://38tera.com/
- Personalised nutrition: https://joinzoe.com/
- Past episodes: https://theproof.com/tag/will-bulsiew...

If you have any additional questions you would like answered in the future, let me know in the comments.

Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test, and a significant discount at http://insidetracker.com/simon.

The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit https://theproof.com/friends/.

Enjoy, friends.
Simon

====

Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit https://theproof.com/friends/

• The Proof with Simon Hill - https://theproof.com/podcast/
• Book: The Proof is in the Plants - https://theproof.com/book/
• Apple Podcast - https://podcasts.apple.com/gb/podcast...
• Spotify - https://open.spotify.com/show/7bAIJCV...
• Instagram -   / theproof  
• Twitter -   / theproof  
• Facebook -   / theproofwithsimonhill  
• Plant-Based Ferments Guide - https://theproof.com/ferments/
• Two-week meal plan - https://theproof.com/mealplan/
• Plant Performance - https://theproof.com/plant-performance/
• Use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.