Local Anaesthetics (Part 02) | Mechanism of Action of Local Anaesthetics Agents | Local Anaesthetic

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The word anaesthesia is coined from two Greek words: "an" meaning "without" and "aesthesis" meaning "sensation". There are various types of anaesthesia. Anaesthesia or anaesthesia (from Greek "without sensation") is a state of controlled, temporary loss of sensation or awareness that is induced for medical purposes. It may include analgesia (relief from or prevention of pain), paralysis (muscle relaxation), amnesia (loss of memory), or unconsciousness. A patient under the effects of anaesthetic drugs is referred to as being anaesthetized.

Anaesthesia enables the painless performance of medical procedures that would otherwise cause severe or intolerable pain to an unanesthetized patient, or would otherwise be technically unfeasible. Three broad categories of anaesthesia exist:
(1) General anaesthesia suppresses central nervous system activity and results in unconsciousness and total lack of sensation.
(2) Sedation suppresses the central nervous system to a lesser degree, inhibiting both anxiety and creation of long-term memories without resulting in unconsciousness.
(3) Regional and local anaesthesia, which block transmission of nerve impulses from a specific part of the body. Depending on the situation, this may be used either on its own (in which case the patient remains conscious) or in combination with general anaesthesia or sedation.

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