Скачать или смотреть Tedizolid; Chemical name, Molecular Formula, Molar mass, Chemical Structure

Chemical Details
Chemical name (IUPAC):
(5R)-3-

\[(2-methyl-1H-pyrazol-5-yl)methyl]-2-oxo-1,3-oxazolidine-5-carboxamide

Molecular formula:
C₁₇H₁₅FN₆O₃

Molar mass:
≈ 370.34 g/mol

Chemical structure (description):
Tedizolid is an oxazolidinone-class antibiotic, structurally related to linezolid but with modifications that enhance potency:

A five-membered oxazolidinone ring (the pharmacophore of this antibiotic class).

A carboxamide substituent at position 5, important for ribosomal binding.

A pyrazole ring attached via a methyl linker, which increases antibacterial activity.

A fluorine atom on the aromatic ring, improving lipophilicity and potency.

Multiple nitrogen atoms in heterocycles, contributing to hydrogen bonding and target specificity.

Several stereocenters, giving it a defined 3D conformation crucial for binding to the bacterial 50S ribosomal subunit

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