BIOCHEMISTRY - CYTOCHROME P450 ENZYMES AND OXIDATION PROCESS

~ What is CYP450 (cytochrome P450 enzymes)
~ CYP450 - Mitchondria and Endoplasmic Reticulum of Hepatic Cells
~ Phase I of Metabolism and excretion
~ Process/Cycle of Oxidation - addition of polar functional groups
~ Biochemistry - chemical reactions to add hydroxyl group to drug

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REFERENCES:

KANDEL, E. R., SCHWARTZ, J. H., & JESSELL, T. M. (2000). Principles of neural science. New York, McGraw-Hill, Health Professions Division

Stahl, S.M. (2013). Mood disorders and antidepressants : Stahl’s essential psychopharmacology. Cambridge: Cambridge University Press.

Cederbaum, A.I. (2017), Chapter 31 - Cytochrome P450 and Oxidative Stress in the Liver, Academic Press, Pages 401-419

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