Neuromyelitis Optica (NMO) [Symptoms, Diagnosis, MRI Findings, Treatment, Clinical Trial Results]

Time stamps:

0:48 Introduction
5:23 Symptoms
6:54 MRI findings
9:11 Diagnosis
11:10 Prognosis
13:52 Differences from MS
16:05 Treatment (attacks)
17:13 Treatment (attack prevention

)Selected Sources:

Review of neuromyelitis optica:https://www.ncbi.nlm.nih.gov/pmc/arti... in NMO: https://pubs.rsna.org/doi/full/10.114...

callosal septal interface lesion:https://www.scielo.br/scielo.php?scri...

evidence based review of treatment of NMO: https://pubmed.ncbi.nlm.nih.gov/22218...

update on diagnosis and treatment of NMO: https://pubmed.ncbi.nlm.nih.gov/24272...

Anti-MOG related disease and NMO: https://pubmed.ncbi.nlm.nih.gov/25257...

Clinical spectrum of NMO: https://pubmed.ncbi.nlm.nih.gov/22459...

Hypothalamic lesions in NMO: https://pubmed.ncbi.nlm.nih.gov/25160...

Satralizumab vs. Placebo: https://www.nejm.org/doi/full/10.1056...

Ineblizumab (Uplizna) vs. Placebo in NMO: https://pubmed.ncbi.nlm.nih.gov/31495...

Eculizumab (soliris) vs. Placebo in NMO: https://www.nejm.org/doi/full/10.1056...

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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles).

He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.

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The video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.