Why Are There so Many C18 LC Columns?

From end-capped to aqueous, there are a multitude of C18 phases to choose from. But why are there so many? A C18 is a C18, right?

In today’s Restek Tip, we’re going to explore the world of C18 phases. Are there benefits to choosing one specific to your analysis? And what parameters should you keep in mind when selecting a phase?

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Additional Resources

A C18 is a C18, right? | https://www.restek.com/chromablograph...

Why do I Lose Retention on my C18 in High Aqueous Mobile Phases? | https://www.restek.com/articles/tech-...

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Restek Recommended Tools & Parts

Raptor C18 LC Columns (traditional, end-capped columns) | https://www.restek.com/search/analyti...

Ultra Aqueous C18 LC Columns (100% aqueous phase columns) | https://www.restek.com/search/analyti...

Raptor ARC-18 LC Columns (sterically-protected, acid resistant columns) | https://www.restek.com/search/analyti...

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