Management of Primary Myelofibrosis with Dr. Ayalew Tefferi

In this episode, we discuss the diagnosis and management of primary myelofibrosis with Dr. Ayalew Tefferi at Mayo Clinic, Rochester, Minnesota. Here are the show notes, including key studies discussed in this episode:

1. Risk stratification of PMF:
MIPSS70 Score: http://www.mipss70score.it
https://pubmed.ncbi.nlm.nih.gov/29226...

Genetically inspired prognostic scoring system (GIPSS):
https://pubmed.ncbi.nlm.nih.gov/29654...

Type 1 CALR mutation:
https://pubmed.ncbi.nlm.nih.gov/25301...

MYSEC-PM:
http://www.mysec-pm.eu
https://pubmed.ncbi.nlm.nih.gov/28561...

2. Treatment of PMF with JAK inhibitors
https://pubmed.ncbi.nlm.nih.gov/36680...

Momelotinib:
https://pubmed.ncbi.nlm.nih.gov/36709...

Pacritinib :
https://ashpublications.org/blood/art...
https://pubmed.ncbi.nlm.nih.gov/29522...

Fedratinib:
https://pubmed.ncbi.nlm.nih.gov/35614...

3. Transplant in PMF
https://pubmed.ncbi.nlm.nih.gov/34889...

Black African-American patients with primary myelofibrosis:
https://pubmed.ncbi.nlm.nih.gov/36780...

4. Imtelestat in PMF
https://pubmed.ncbi.nlm.nih.gov/26332...