NEUROMUSCULAR BLOCKING AGENTS - Paralytics (Part 2) - ICU Drips

In this next lesson on ICU Drips and Paralytics, we take a look at the different neuromuscular blocking agents that we have at our disposal in the ICU. We start off talking about the 2 different categories of these medications, the depolarizing and non-depolarizing agents.

For our depolarizing agents, they bind the Ach receptors and activate them initially before staying bound to block future activation. The only medication that we use in this category is a medication called Succinylcholine. It is important to know that while this medication has many useful benefits, there are some serious side effects as a result of being a depolarizing agent.

Next we talk about our non-depolarizing agents. These medications bind Ach receptors and block them but do not initially active them when bound. We have 2 different classes of these medications, the Aminosteroids and the Benzylisoquinoliniums. We also usually group these medications by their length of action. We don't have any short-acting medications in this category, but when looking at the intermediate-acting medications we have 2 aminosteroids and 2 benzylisoquinolinium. The 2 aminos are Rocuronium and Vecuronium, and the 2 benzyls are Atracurium, which really isn't used much anymore, and Cisatracurium, also known as Nimbex. Nimbex is our most commonly used medication when it comes to a continuous infusion. Finally we talk about our sole long-acting medication called Pancuronium.

Hopefully after this lesson you will have a better understanding of the different medications that we use for neuromuscular blockage and some of the key difference between them, so that hopefully you will feel more comfortable with their use in the ICU.

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Don't forget to check out the playlist for this series of lessons here:    • ICU Drips  

Also check out these other great lessons and series of lessons below!

Hemodynamics Principals:    • Hemodynamic Principals  
Shock:    • Shock  
Arterial Blood Gases:    • Arterial Blood Gases (ABGs)  
ECG/EKG Rhythm Interpretation:    • ECG/EKG Interpretation  
Heart Failure:    • Heart Failure  
Endocrine System:    • Endocrine System  

Blood Tubes - Order of Draw:    • Order of Draw and Additives | Blood C...  
Glasgow Coma Scale:    • Glasgow Coma Scale (GCS) Assessment  

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