How do fibrils form?

Fibrils are implicated in neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Using gold nanoparticles to ‘freeze’ peptides at the point they start to form fibrils can give us valuable insight into how these damaging particles form. This study was conducted at the undergraduate institution, State University of New York – Geneseo College, with a very limited research budget. In order to conduct a good quality study, the method was carefully designed and a good amount of time spent on the data analyses, combining a mathematical approach with chemical knowledge. Using gold nanoparticles allowed the team to demonstrate how proteins bond to each other.
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https://www.geneseo.edu/chemistry/yok...
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