Synthetic Peptide Libraries Part 1: Dr. Christian Behn

Basics of peptide libraries and strategies for design and synthesis, Dr. Christian Behn

The rapidly increasing demand for synthetic peptides in research calls for extremely efficient automated synthesizers. Synthetic peptides are essential tools for a wide range of biochemical experiments. They are used for primary screening in drug development, for development of synthetic vaccines, peptide-based diagnostic procedures, and for basic research in molecular biology. Peptide libraries are systematic sets of overlapping peptides for simple functional assays and highly advantageous in the identification of target peptides and accommodate a whole spectrum of applications. This is useful for binding studies, epitope mapping, and protein-protein interactions. Peptides are excellent drug candidates because of their ability to bind to their targets with high specificity and affinity. Peptide libraries can even lead to the discovery of potential biomarkers within clinical trials.