DMT in the Brain: A Pharmacologist's Perspective

Dimethyltryptamine, or DMT, is a potent psychedelic drug commonly found in nature. Some suggest DMT is also produced by our brains and contribute to a wide variety of experiences. Scientists have also been intrigued by the possibility that DMT would be involved in, for example, psychiatric disorders and the generation of psychedelic experiences or dreamlike states. In this video, I will briefly examine the physiological function of putative endogenous DMT from a pharmacological perspective.

I'd be happy to hear your thoughts about this matter and continue the discussion down below in the comments section.

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Further reading:

N,N-dimethyltryptamine and the pineal gland: Separating fact from myth
David E Nichols
PMID: 29095071 DOI: 10.1177/0269881117736919

The Eye of Horus: The Connection Between Art, Medicine, and Mythology in Ancient Egypt
Karim ReFaey, Gabriella C Quinones, William Clifton, Shashwat Tripathi, and Alfredo Quiñones-Hinojosa
PMID: 31355090 DOI: 10.7759/cureus.4731

N, N-Dimethyltryptamine (DMT), an Endogenous Hallucinogen: Past, Present, and Future Research to Determine Its Role and Function
Steven A Barker
PMID: 30127713 DOI: 10.3389/fnins.2018.00536

--- Added 26.7.2023

*A study of DMT in the Rat brain:

Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DMT) in Mammalian Brain
Jon G Dean et al.
PMID: 31249368 DOI: 10.1038/s41598-019-45812-w

*A Critique of the study of DMT in the Rat brain by the Nichols: https://www.aliusresearch.org/nichols...

#dmt #pinealgland #psychedelic