Edman Degradation

Описание к видео Edman Degradation

The Edman degradation takes advantage of unique nucleophilic reactivity of the N-terminal amino group to determine the sequence of a polypeptide from N-terminus to C-terminus, residue by residue.

00:00 Introduction
00:55 Cleavage and Cyclization by PIC
02:47 Mechanism of Cleavage by PIC
04:54 Summary

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